CERTIFIED SERUM
Certified FBS is our traditional, high quality FBS and meets the requirements of the 
most discriminating FBS users.  Over 50 tests are carried out and recorded on the 
Certificates of Analysis. Please request a certificate of analysis from info@biosera.com.

Product code         Country of Origin
S1520                     North America 
S1600                     Central America 
S1650                     Mexico
S1700                     Australia 
S1750                     Denmark 
S1810                     South America - Paraguay, Uruguay, Chile, Brazil, Argentina, Columbia
S1820                     France

Note: All mother bovine from France and Denmark over the age of 30 months are tested for BSE. 

SPECIAL CERTIFIED SERUM
Biosera offers specially treated/tested Certified FBS to meet customers' specific requirements. 
If you require a treatment not listed here, please contact your local Biosera office or Distributor. 
Special Certified serum is available from all the origins listed above. 


If sera is required with any of the following treatments, please ensure that the specific treatment
is stated when ordering. Omissions cannot be rectified at a later date. 

CHARCOAL STRIPPED FBS
Product codes: S152F, S160F, S1650F, S170F, S175F, S181F, S182F

DOUBLE CHARCOAL STRIPPED
Product codes: S152X, S160X, S1650X, S170X, S175X, S181X, S182X

FBS treated with charcoal activated dextran has reduced levels of various hormones and other 
factors, making it useful for assaying cells used in receptor and other signal related studies

DIALYSED FBS
Product codes: S152D, S160D, S1650D, S170D, S175D, S181D, S182D

FBS is dialysed against an osmo-equivalent saline solution using membranes with a cut-off 
rated at 10,000 Daltons. The concentration of small components such as ions, salts, nucleotides, 
amino acids, vitamins, some hormones and other metabolites is substantially reduced.

STEM CELL TESTED FBS
Product codes: S152S, S160S, S1650S, S170S, S175S, S181S, S182S 

Our highest quality FBS lots are screened for use with stem cells. Using cells specifically grown 
by a leading stem cell company, we assay these lots for growth rate, plating efficiency, colony 
morphology and toxicity.

LOW IgG FBS
Product codes: S152I, S160I, S1650I, S170I, S175I, S181I, S182I

The level of IgG in FBS is normally low but can increase significantly if there has been an immune 
challenge to the mother. By screening each sample of FBS with an IgG ELISA we identify and pool 
those samples with very low levels of IgG. Low IgG FBS is especially useful for the production of 
monoclonal antibodies. The purification of some target proteins can also be improved by the use 
of Low IgG FBS. By sourcing naturally low IgG FBS, Biosera avoids the need to chemically treat 
the serum maintaining a higher quality and simplifying customers' regulatory process.

LOW LIPID FBS
Cholesterol, Triglycerides and Phospholipids are removed by treating the FBS with a product 
called Liposorb.

GAMMA IRRADIATED FBS
Product codes: S152G, S160G, S1650G, S170G, S175G, S181G, S182G

Serum is l-irradiated by a 60Co source with 25kGy to eliminate mycoplasma and l-radiation 
sensitive viruses.

TETRACYCLINE FREE FETAL BOVINE SERUM
Product codes: S175T, S182T

Biosera tests batches of sera for the absence of Tetracycline. Currently only Danish and French 
are tested.  Other origins can be tested on request. 

QUALIFIED FETAL BOVINE SERUM
Product code: S1900 (old code S1870)

For customers working with robust cells or under budget constraints, Biosera offers 
Qualified serum. Qualified serum is processed similarly to Certified FBS but does not 
undergo the same level of testing. All serum is routinely tested for sterility, mycoplasma 
and viruses but the Qualified serum is only tested for its cell growth properties. The 
lowered cost associated with producing this serum allows Biosera to offer it at a discount.
           

HEAT INACTIVATION:

Sera is Incubated at 56oC for 30 minutes to inactivate the compliment cascade.